Elizabeth Head, PhD

 
   
Positions:  

Assistant Professor

Degrees:  

B.Sc. (Neuroscience), University of Toronto, 1991
M.A. (Psychology), University of Toronto, 1992
Ph.D. (Neuroscience), University of Toronto, 1997

Research Interest:

 

Aging brain, Alzheimer’s disease, Down syndrome, Canine model of human brain aging, antioxidant interventions
 

Professional Societies:

 

Society for Neuroscience

Honors :   Honors List, University of Toronto, 1991
University of Toronto Open Masters Fellowship, 1992
University of Toronto Open Doctoral Fellowship, 1993
Scarborough Campus Graduate Student Award (Ph.D. level) - 1996.

Publications:

 

Head, E ., B.Y.. Azizeh, I.T. Lott, A.J. Tenner, C.W. Cotman, and D.H. Cribbs. (2001). Complement association with Neurons and b -Amyloid Deposition in the Brains of Aged Individuals with Down syndrome. Neurobiology of Disease, 8: 252-265.

Head, E . (2001) Brain Aging in Dogs: Parallels with Human Brain Aging and Alzheimer’s disease. Veterinary Therapeutics, 2(3): 247-260.

Head, E., Garzon-Rodriguez, W., Johnson, J.K., Lott, I.T., Cotman, C.W. and Glabe, C.G. (2001) Oxidation of A b and plaque biogenesis in Alzheimer’s disease and Down Syndrome. Neurobiology of Disease, 8: 792-806.

Cotman, C.W., Head, E., Muggenburg, B.A., Zicker, S., and Milgram, N.W. (2002). Brain aging in the canine: A diet enriched in antioxidants reduces cognitive dysfunction. Neurobiology of Aging, 23: 809-818.

Head, E ., Liu, J., Hagen, T.M., Muggenburg, B.A., Milgram, N.W., Ames, B.N., and Cotman, C.W. (2002) Oxidative damage increases with age in a canine model of human brain aging. Journal of Neurochemistry, 82: 375-381.

E. Head , I.T. Lott, D.H. Cribbs, C.W. Cotman and T.T. Rohn (2002). b -Amyloid deposition and neurofibrillary tangle association with caspase activation in Down syndrome. Neuroscience Letters, 330: 99-103.

R. Kayed, E. Head, J.L. Thompson, T. M. McIntire, S.C. Milton, C.W. Cotman and C. G. Glabe ( 2003). Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis. Science, 300: 486-489.

Haier, RJ, Alkire, Mt, White, NS, Uncapher, I, Lott, IT, Head, E & Cotman,CW. (2003)Temporal cortex hyper-metabolism in Down syndrome prior to the onset of dementia, Neurology, 61(12): 1673-1679.

E. Head , I.T. Lott,P.R. Hof, C. Bouras, J.H.Su, R. Kim, R. Haier and C.W. Cotman (2003). Compensatory and Pathological events Associated with Tau Pathology in Middle Aged Individuals with Down Syndrome. Journal of Neuropathology and Experimental Neurology, 62(9): 917-926.

Head, E ., Lott I.T. (2004). Down syndrome and Beta-Amyloid. Current Opinion in Neurology. 17(2) 95-100.


     
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