My major interests center around issues of science policy.  These include topics such as ethical issues in research, the funding of medical research, conflicts between public expectations and research priorities, and publication policy for research information.
My previous laboratory research program followed two closely related themes: the in vitro regulation of cytotoxic cells by cell interactions, cytokines, and other regulatory factors and the in vivo expression of cytotoxic cell function in cancer patients. The major focus of these studies was the regulation and expression of cytotoxicity mediated by human Natural Killer (NK) lymphocytes.

Selected Publications:

Science policy. The NIH budget in the "postdoubling" era. Korn D, Rich RR, Garrison HH, Golub SH, Hendrix MJ, Heinig SJ, Masters BS, Turman RJ, Science 2002 May 24 296:5572 1401-2

Sidney H. Golub, Electronic Darwinism. FASEB J. 2001, 15:1117.

Sidney H. Golub, The Golden Age of Biomedical Research. FASEB J. 2000, 14:1.

Rhoades, Kristina L, Golub, Sidney H., and Economou, James S. The adenoviral transcription factor, E1A 13S, trans-activates the human tumor necrosis factor-alpha promoter. Virus Research, 40:65-74, 1996.

Rhoades, Kristina L., Cai, Sanjun, Golub, Sidney H., and Economou, James S. Granulocyte-macrophage colony-stimulating factor and interleukin-4 differentially regulate the human tumor necrosis factor-alpha promoter region. Cell. Immunol. 161:125-131 1995.

Sarna, G., Machleder, H., Collins, J., Bonavida, B., Jacobs, E., Hawkins, R., Golub, S.H., Shau, H., Fahey, J.L., Popow, J., Robertson, P., Ahn, S., and Quinones, W.  A comparative study of intravenous versus intralymphatic interleukin-2 upon both peripheral blood and thoracic duct lymph.  J. Immunothera. 15:140-146, 1994.

Dadmarz, R., Bockstoce, D., and Golub, S.H.  Interleukin-7 Selectively Enhances Natural Killer Cytotoxicity Mediated by the CD56bright Natural Killer Subpopulation.  Lymphokine and Cytokine Research.  13:349-357, 1994.

List of Publications via PubMed (NIH National Library of Medicine)