Publications (selected)

Ty3 position specificity

Ty3 retrotransposition and host genes

Lab Members

Former Labbies

Contact Us

Publications

Sandmeyer CV

Methods

Links

Hansen, L., Chalker, D. and Sandmeyer, S. (1988) Ty3, A yeast retrotransposon with homology to animal retroviruses inserts next to tRNA genes. Mol. Cell. Biol. 8, 5245-5256.

Hansen, L. J. and Sandmeyer, S. B. (1990) Characterization of a transpositionally active Ty3 element and identification of the Ty3 integrase protein. J. Virol. 64, 2599-2607.

 Chalker, D. L. and Sandmeyer S. B. (1990) Transfer rna genes are genomic targets for de novo transposition of the yeast retrotransposon Ty3. Genetics 126, 837-850.

Hansen, L. J., Chalker, D. L., Orlinsky, K. J. and Sandmeyer, S. B. (1992) Ty3 GAG3 and POL3 genes encode the components of intracellular particles. J. Virol. 66, 1414-1424.

Chalker, D. L. and Sandmeyer, S. B. (1992) Ty3 Integrates within the region of RNA polymerase III transcription initiation. Genes Dev. 6, 117-128

Kirchner, J., Connolly, C. and Sandmeyer, S.B. (1995) Requirement of Rna polymerase iii transcription factors for in vitro position-specific integration of a retroviruslike element. Science 267, 1488-1491.

Connolly, C and Sandmeyer, S.B. (1997) RNA polymerase III interferes with Ty3 integration. FEBS Letters 405, 305-311.

Dildine, S.L. and Sandmeyer, S.B. (1997) Integration of the yeast retrovirus-like element Ty3 upstream of a human tRNA gene expressed in yeast. Gene 194, 227-233.

Gu, J., Emerman, M. and Sandmeyer, S.B. (1997) Small heat shock protein suppression of Vpr-induced cytoskeletal defects in budding yeast. Mol. Cell. Biol. 17, 4033-42.

Dildine, S.L., Respess, J. Jolly, D. and Sandmeyer, S.B. (1998) A chimeric Ty3/Moloney murine leukemia virus integrase protein is active in vivo. J. Virol. 72, 4297-4307.

Sandmeyer, S.B. (1998) Targeting transposition: at home in the genome. Genome Research 8: 416-418.

Nymark, H. and Sandmeyer, S.B. (1999) Mutations in  non-conserved domains of Ty3 integrase affect multiple stages of the Ty3 life cycle. J. Virology, 73, 453-465.

Hu, Y-J., Sandmeyer, S.B., and Kibler, D. (1999) Detecting motifs from sequences.  Proceedings of the International Cong. on Machine Learning.  Bleb, Slovenia.

Rausch, J.W., Bona-Le Grice, M.K., Nymark-McMahon, M. H. (graduate student), Miller, J.T., and Le Grice, S.F.J.  (2000) Interaction of p55 reverse transcriptase from the Saccharomyces cerevisiae retrotransposon Ty3 with conformationally distinct nucleic acid duplexes. J. Biol. Chem. 275, 13879-13887.

Hu, Y. J., Sandmeyer, S., McLaughlin, C., Kibler, D. (2000)  Combinatorial motif analysis and hypothesis generation on a genomic scale. Bioinformatics. 16, 222-32.

Yieh, L., Kassavetis, G., Geiduschek, E.P., Sandmeyer, S.B. (2000) The Brf and TATA Binding subunits of the RNA polymerase III transcription factor IIIB mediate position-specific integration of the gypsy-like Element, Ty3. J Biol Chem. 275, 29800-29807.

Hampson, S., Baldi P., Kibler, D., Sandmeyer, S.B.  (2000) Analysis of yeast ORF upstream regions by parallel processing, microarrays, and computational methods. ISMB  8,190-201.

Claypool, J.A., Malik, H.S., Eickbush, T.H., and Sandmeyer, S.B.  (2001) A 10 kDa domain in Ty3 Gag3-Pol3p between PR and RT is dispensable for Ty3 transposition. J. Virol. 75, 1557-1560.

Aye, M., Dildine, S.L., Claypool, J.A., Jourdain, S. and Sandmeyer, S.B.  (2001) A truncation mutant of the 95 kD subunit of transcription factor IIIC reveals asymmetry in Ty3 integration. Mol. Cell. Biol. 21, 7839-7851.

Lin, S., Nymark-McMahon, M. H., Yieh, L., and Sandmeyer, S.B.  (2001) Integrates mediates nuclear localization of Ty3.  Mol. Cell. Biol. 21, 7826-7838.

Nymark-McMahon, M. H., Beliakova-Bethell, N.S., Darlix, J-L., Le Grice, S.F.J., and Sandmeyer, S.B. (2002) Ty3 integrase is required for initiation of reverse transcription.  J. Virol. 76, 2804-2816.

Sandmeyer, S., Aye, M., and Menees, T.  (2002) Ty3: A position-specific, gypsylike element in Saccharomyces cerevisiae.  In Mobile DNA, ASM Press, Washington DC.

Yieh, L., Hatzis, H., Kassavetis, G., Geiduschek, E.P. Sandmeyer, S.B. (2002) Mutational analysis of the TFIIIB-DNA target of Ty3 retroelement integration.  J. Biol. Chem. 277, 25920-25928.

Nagy, A., Perrimon, N., Sandmeyer, S.B., and Plasterk, R. (2002) Gene manipulation.  Nat. Gen. Sup. (Tenth Year Anniversary Issue) 33: 276-284.

Sandmeyer, S.B. (2003) Integration by design (Commentary)  Proc. Natl. Acad. Sci. USA 100:5586-5588.

Aye, M. and Sandmeyer, S.B. (2003) Ty3 requires yeast La homologous protein for wild-type frequencies of transposition.  Mol. Microbiol. 49, 501-515.

Aye, M. Irwin, B., Archibald, H., and Sandmeyer, S.B. (2004) Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae.  Genetics 168, 1159-1176.

Irwin, B., Aye, M., Baldi, P., Beliakova-Bethell, N., Cheng, H., Dou, Y., Liou, W. and Sandmeyer, S.B. 2005. Retroviruses and yeast retrotransposons use overlapping sets of host genes. Gen. Res. 15:641-654.

Kuznetsov, Y.G., Zhang, M., Menees, T.  McPherson, A, and Sandmeyer, S..  (2005) Atomic force microscopy investigation of the structure of Ty3 retrotransposon particles. J. Virol. 79: 8032-8045.

Beliakova-Bethell, N., Beckham, C., Giddings, T.H. Jr., Winey, M., Parker, R., and Sandmeyer, S. (2006) Virus-like particles of the Ty3 retrotransposon assemble in association with P-body components.  RNA 12:94-101.