|
Researcher |
Area of Research |
|
Wen-Hwa Lee Program Director Donald Bren Professor of
Biomedicine and Chair, Department of Biological
Chemistry |
Dr.
LeeÕs team is involved in the study of tumor suppressor genes as well as
developing small compounds offer a potential to develop new combinatorial
treatment with chemotherapy or radiation therapy. http://www.healthaffairs.uci.edu/biochem/whlee/index.html |
|
Bruce Blumberg Associate Professor Departments of Developmental &
Cell Biology and Biomedical Engineering |
The Blumberg laboratory is
broadly interested in the study of gene regulation and intercellular
signaling. Researchers in the Blumberg laboratory study a family of
ligand-modulated transcription factors, the nuclear hormone receptors, and
their role in embryonic development, adult physiology and diseases such as
cancer. http://blumberg-lab.bio.uci.edu/ |
|
Peter Bryant Professor, Developmental &
Cell Biology Director, Developmental Biology
Center |
The
objective of Dr. BryantÕs lab is to understand how cell proliferation is
controlled during development, and how genetic mutations lead to growth
abnormalities and cancer. http://mamba.bio.uci.edu/~pjbryant/dbc/bryantp.htm |
|
Paulo Casali Donald Bren Professor of Medicine Departments of Medicine and Molecular Biology &
Biochemistry Director, Center for Immunology |
Dr.
CasaliÕs laboratory is doing research in molecular immunology and genetics. |
|
Richard Chamberlin Professor, Chemistry (School of
Physical Sciences), Professor & Chair,
Pharmaceutical Sciences |
Chemical
synthesis is the central tool in the Chamberlin teamÕs general objective of
controlling the biological activities of important target proteins with new
small molecule ligands. Current objectives include neurotransmitter
receptors, serine-threonine phosphatases, potassium channels, HIV integrase,
and the tumor suppressor p53. http://chem.ps.uci.edu/~archambe/ |
|
John Fruehauf Associate Clinical Professor, Medicine
– Hematology/Oncology |
My group has focused on mechanisms of drug action and resistance
with the goal of improving therapeutic outcomes for cancer patients. Active
areas in my laboratory include the role of glutathione and redox mechanisms
in drug action, the regulation and targeting of vascular endothelial cells,
and differential gene expression related to drug resistance. |
|
Randy Holcombe Professor, Department of Medicine Chief, Division of Hematology/Oncology |
Cancer
Immunology, Wnt Signaling in Cancer and Clinical and Translational Research
are the research areas of Dr. HolcombeÕs group. http://www.ha.uci.edu/som/deptmed/?p=80 |
|
Peter Kaiser Associate Professor, Biological
Chemistry |
Dr. Kaiser studies cell cycle control and
regulation of proteins by ubiquitination. http://www.healthaffairs.uci.edu/biochem/faculty/kaiser.html |
|
Eva Lee Professor, Biological
Chemistry/Developmental & Cell Biology |
Dr. Eva LeeÕs research interests include cell cycle
checkpoint pathways and molecular genetics studies of breast cancer using
mouse model systems http://www.healthaffairs.uci.edu/biochem/faculty/evalee.html |
|
Steve Lipkin Associate Professor, Biological
Chemistry and Medicine, Hematology/Oncology |
Dr. Lipkin's laboratory studies the new chemoprevention and
chemotherapy targets in colon cancer initiating stem cells. http://www.healthaffairs.uci.edu/biochem/faculty/lipkin.html |
|
Frank Professor, Medicine – Hematology/Oncology and Biological Chemistry Director, Chao Family
Comprehensive Cancer Center |
The
long term interest of Dr. Meyskens laboratory has been the development of
experimental and clinical therapies of melanoma based on knowledge of the transformation process. Current
efforts are focused on characterizing the role of the master redox-sensitice
transcription factor Ref-1 and the
chemoprevention of human cancer. http://www.healthaffairs.uci.edu/biochem/faculty/meyskens.html |
|
Daniele Piomelli Professor, Pharmacology Louise Turner Arnold Chair of
Neurosciences |
Research
in the Piomelli lab is focused on the function of lipid-derived messengers,
with particular emphasis on the endogenous cannabinoids anandamide and
2-arachidonoylglycerol. Current research efforts converge on three areas:
formation and deactivation of anandamide and 2-arachidonylglycerol;
physiological roles of the endogenous cannabinoid system; development of therapeutic
agents that target anandamide and 2-arachidonylglycerol metabolism.
|
|
Eric Stanbridge Professor, Microbiology &
Molecular Genetics |
Eric StanbridgeÕs research focuses on identifying tumor
suppressor genes and oncogenes (which transform normal cells into cancerous
tumor cells), and understanding their interactive functions in human cancer. |
|
Doug Wallace Donald Bren Professor of Molecular Genetics Department of Biological Chemistry Director, Center for Molecular and
Mitochondrial Medicine and Genetics |
Dr.
WallaceÕs lab is developing medications, called catalytic antioxidants, which
help mitigate damage done to the mitochondria when mtDNA mutations
accumulate. http://www.faculty.uci.edu/profile.cfm?faculty_id=5235 |
|
Marian Waterman Professor, Microbiology &
Molecular Genetics |
Dr.
Waterman is research is in the regulation of gene expression by
LEF/TCF¥b-catenin complexes. |
|
Kyoko Associate Professor, Biological
Chemistry |
The
Yokomori Lab studies the role of SMC family proteins in chromosome dynamics. |
