Our faculty members are dedicated to teaching and inspiring our graduate, post-doctoral and medical students. Areas of research focus range from cancer biology to molecular and cellular biology within several model systems. Please click on individual Principal Investigators link for specific details.


Drs. Wen-Hwa Lee ,Douglas Wallace and Eva Lee
Wen-Hwa Lee, Donald Bren Professor of Biomedicine and Dept Chair

Ph.D., University of California, Berkeley, 1981

A pioneer in the research on tumor-suppressor genes and why the repair mechanisms for DNA can fail and cause subsequent accumulations of cancer-promoting mutations.

Bogi Andersen, Associate Professor, Department of Medicine

M.D., University of Iceland, 1981

Transcriptional regulation in normal and diseased epithelia

Pierre Baldi, Chancellor's Professor, Department of Computer Science and Director, Institute for Genomics and Bioinformatics

Ph.D. Mathematics, California Institute of Technology, 1986

Bioinformatics / Computational Biology /Systems Biology / Chemoinformatics / Drug Discovery

Probabilistic Modeling / Machine Learning /Statistical Datamining

Phang-Lang Chen, Associate Professor

Ph.D., University of California, San Diego, 1991

Critical role of tumor suppressor genes in the genesis and progression of cancer

Xing Dai, Associate Professor

Ph.D., University of Chicago, Chicago, Illinois, 1995

Role of the regulatory proteins Ovo in germ cell and epidermal differentiation

Peter Donovan, Professor, Developmental and Cell Biology

Ph.D., University College, London 1989

Peter Kaiser, Associate Professor

Ph.D. University of Innsbruck, Austria, 1994

Control of the cell cycle through mechanisms involving ubiquitination

Eva Y.-H. P. Lee, Professor

Ph.D., University of California, Berkeley, 1984

Cell cycle checkpoint pathways and molecular genetics studies of breast cancer using mouse model systems

Leonid E. Lerner, Assistant Professor, Department of Ophthalmology

Ph.D., University of California, Los Angeles

Ellis R. Levin, Professor, Department of Medicine

M.D., Jefferson Medical School, 1975

The plasma membrane estrogen receptor (ER) and its effects on the biology of estrogen action

Steve Lipkin, Associate Professor , Department of Medicine

M.D./Ph.D.

DNA mismatch repair (MMR) is critical for maintaining both mitotic and meiotic genomic integrity.

Haoping Liu, Professor

Ph.D., Cornell University, 1991

MAP kinase mediated signal transduction; dimorphic regulation in yeast.

Leslie Lock, Asst. Adj.Professor, Developmental and Cell Biology

Ph.D., University of California, San Francisco 1985

Calvin S. McLaughlin, Professor

Ph.D., Massachusetts Institute of Technology, 1964

Macromolecule biosynthesis; control of cell division

Frank L. Meyskens, Professor

M.D., University of California, San Francisco, 1972

Biology of human melanocytes and melanomas

Robert K. Moyzis, Professor and Human Genomics Coordinator for the Institute for Genomics and Bioinformatics

Ph.D., The Johns Hopkins University, 1978

Chromosome structure and gene expression; Human telomere and centromere organization and function.

Masayasu Nomura, Grace Bell Professor

Ph.D., University of Tokyo, 1957

RNA Polymerase I; nuclear transport and function

Daniele Piomelli, Professor and Louise Turner Arnold Chair in Neurosciences, Pharmacology

Ph.D., Columbia University

cellular pharmacology, neuropharmacology

Suzanne Sandmeyer, Professor and Director, UCI DNA and Protein MicroArray Facility

Ph.D., University of Washington, 1980

Molecular genetics of a position-specific yeast retrovirus-like element

Rob Steele, Associate Professor

Ph.D., Yale University, 1980

Molecular biology of Hydra development

Leslie Thompson, Associate Professor, Department of Psychiatry and Human Behavior

Ph.D., University of California, Irvine, 1988

Human genetic disorders

Paul Vrana, Assistant Professor

Ph.D. Columbia University, 1994

Control of mammalian growth through imprinting

Doug Wallace, Professor

Ph.D.

Sara T. Winokur, Associate Researcher

Ph.D., University of California, Irvine, 1995

Molecular pathogenesis of facioscapulohumeral muscular dystrophy (FSHD)

Kyoko Yokomori, Associate Professor

Ph.D., University of Southern California, 1991

Mechanism and regulation of chromosome structural changes required for the maintenance of genome integrity